European health authorities are urging doctors to be more cautious when prescribing a type of antibiotics that is regularly used for the treatment of certain urinary tract infections, known as fluoroquinolones. The reminder follows concerns about rare but serious side effects, and updated guidance from both the European Medicines Agency (EMA) and the European Association of Urology (EAU).
Fluoroquinolones have long been used to treat a variety of infections. But in recent years, evidence has shown that they can sometimes cause lasting harm, including tendon damage, nerve problems, and muscle pain. These reactions may appear just days after starting treatment, but in some cases they can emerge months later and may be irreversible.
Back in 2019, the European Commission introduced new restrictions on when fluoroquinolones can be prescribed. Since then, doctors across Europe have been advised to reserve these drugs for situations where other, safer antibiotics do not work. The EMA also required clearer warnings for patients, so that anyone experiencing unusual symptoms knows to stop treatment and seek medical advice quickly.
Now, the European Association of Urology has echoed those warnings. Its latest guidelines recommend that fluoroquinolones should not be used to prevent infections before a prostate biopsy or to treat simple bladder infections, also known as cystitis. According to urology experts, safer and equally effective alternatives are available in both cases.
“Fluoroquinolones still have an important role in treating serious infections,” says Professor [Insert Name], chair of the EAU Guidelines Panel on Infections. “But the risks mean they should be used with care, and only when no other options are suitable.”
For patients, the advice is simple: if you are prescribed a fluoroquinolone, be alert for warning signs such as tendon pain, tingling, or numbness. These could indicate the start of a side effect, and it is important to contact a doctor immediately rather than continuing the medication.
By tightening prescribing rules and raising awareness, European health bodies hope to protect patients from avoidable harm while ensuring that these antibiotics remain effective when they are truly needed.
Posted: 20/08/2025
